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LLY · Forward model · Oncology

What has to happen in Oncology

Model as of

This page changes Oncology inside the complete LLY model. Every other vertical, corporate programme and valuation assumption stays in the selected portfolio case.

LLY forward model
Horizon
Consolidated fair value $678.07 all other verticals held in this portfolio case
Final-quarter revenue $3.30B 10% of company revenue
Explicit segment contribution $19.83B EBITDA less segment capex, before corporate items

Oncology

Basis quarter$2.57B
Final quarter$3.30B
Implied CAGR+5%
Final revenue mix10%

Verzenio plus a broadening portfolio - Jaypirca, Retevmo and the 2026 launch Inluriyo. At $2,570M it is 11.2% of revenue and grew 6.5% year over year, so it is ballast rather than growth: it funds the pipeline without changing the terminal value.

Last four quarters
2025 Q3 $2.41B Reported
2025 Q4 $2.61B Estimated
2026 Q1 $2.27B Reported
2026 Q2 $2.57B Reported
VerzenioJaypircaInluriyoother oncology
Sequential growth +1.6%/qtr decaying toward +1.0% 1.6% deseasonalised, the average of the last four quarters on that series (+6.8%, -0.2%, -0.4%, +9.7%, then -2.4%).
Oncology

Latest: $3.30B (2031Q2E)

Period Value
2024Q1 $1.81B
2024Q2 $2.16B
2024Q3 $2.23B
2024Q4 $2.55B
2025Q1 $1.95B
2025Q2 $2.41B
2025Q3 $2.41B
2025Q4 $2.61B
2026Q1 $2.27B
2026Q2 $2.57B
2026Q3E $2.61B
2026Q4E $2.88B
2027Q1E $2.32B
2027Q2E $2.73B
2027Q3E $2.76B
2027Q4E $3.05B
2028Q1E $2.45B
2028Q2E $2.88B
2028Q3E $2.91B
2028Q4E $3.21B
2029Q1E $2.57B
2029Q2E $3.02B
2029Q3E $3.05B
2029Q4E $3.36B
2030Q1E $2.69B
2030Q2E $3.16B
2030Q3E $3.19B
2030Q4E $3.51B
2031Q1E $2.82B
2031Q2E $3.30B

Assumptions & reasoning

  • Seasonality [0.876, 1.017, 1.016, 1.105] is the cleanest shape in the company: a 12% Q1 trough and a 10% Q4 peak, stable to within 0.023 across the two eight-quarter windows with residual noise of 0.022 log-points. It is consistent with US buy-and-bill oncology behaviour around benefit-year resets.
  • Verzenio is flat to slightly down in the US - 2026 Q2 US revenue $845M against $929M a year earlier - with outside-US growth carrying the line.
  • Inluriyo is a 2026 launch and booked $75M in the basis quarter, its second quarter of sales; it is inside this line, not broken out.
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