Fund · 13F archive
Baker Bros. Advisors LP — 2026 Q1 holdings
Period end
Filed
Portfolio value
$17.42B
Positions
84
We track
1
| # | Company | Class | Value | Shares | % Port. | vs prior |
|---|---|---|---|---|---|---|
| 1 | Incyte Corporation | COM | $2.89B | 30.7M | 16.6% | ADD |
| 2 | Beone Medicines LTD. | SPONSORED ADS | $2.61B | 8.8M | 15.0% | HOLD |
| 3 | Insmed Incorporated | COM PAR $.01 | $1.21B | 7.4M | 7.0% | ADD |
| 4 | Madrigal Pharmaceuticals, INC. | COM | $1.12B | 2.1M | 6.4% | HOLD |
| 5 | Acadia Pharmaceuticals INC. | COM | $954.9M | 42.9M | 5.5% | HOLD |
| 6 | Revolution Medicines, INC. | COM | $929.3M | 9.6M | 5.3% | ADD |
| 7 | Celcuity INC. | COM | $903.5M | 7.9M | 5.2% | HOLD |
| 8 | Kodiak Sciences INC. | COM | $759.3M | 19.9M | 4.4% | HOLD |
| 9 | Kymera Therapeutics, INC. | COM | $721.1M | 8.7M | 4.1% | HOLD |
| 10 | Summit Therapeutics INC. | COM | $690.0M | 36.4M | 4.0% | HOLD |
| 11 | Praxis Precision Medicines, INC. | COM | $564.9M | 1.8M | 3.2% | ADD |
| 12 | Rhythm Pharmaceuticals, INC. | COM | $487.4M | 5.6M | 2.8% | HOLD |
| 13 | Alkermes Plc | SHS | $354.0M | 10.0M | 2.0% | HOLD |
| 14 | Grail, INC. | COM | $208.2M | 4.0M | 1.2% | ADD |
| 15 | Edgewise Therapeutics, INC. | COM | $207.1M | 6.6M | 1.2% | HOLD |
| 16 | Ionis Pharmaceuticals, INC. | COM | $153.8M | 2.0M | 0.9% | ADD |
| 17 | Kiniksa Pharmaceuticals International, Plc | ORD SHS CL A | $136.1M | 2.8M | 0.8% | HOLD |
| 18 | Immunovant, INC. | COM | $135.6M | 5.5M | 0.8% | HOLD |
| 19 | Roivant Sciences LTD. | SHS | $134.8M | 4.9M | 0.8% | TRIM |
| 20 | Ideaya Biosciences, INC. | COM | $131.5M | 3.9M | 0.8% | ADD |
| 21 | Arrowhead Pharmaceuticals, INC. | COM | $124.9M | 2.0M | 0.7% | TRIM |
| 22 | Stoke Therapeutics, INC. | COM | $108.6M | 3.3M | 0.6% | HOLD |
| 23 | Immatics N.V. | SHS | $107.4M | 10.9M | 0.6% | TRIM |
| 24 | ABCLAbCellera Biologics Inc.★ | COM | $105.7M | 30.3M | 0.6% | ADD |
| 25 | Abivax S.A. | SPONSORED ADS | $97.5M | 876K | 0.6% | HOLD |
| 26 | Crinetics Pharmaceuticals, INC. | COM | $85.4M | 2.4M | 0.5% | ADD |
| 27 | Replimune Group, INC. | COM | $84.5M | 11.0M | 0.5% | HOLD |
| 28 | Celcuity INC. | Note 2.75% 8/1/2031 | $74.9M | 30.8M | 0.4% | HOLD |
| 29 | Nurix Therapeutics, INC. | COM | $72.2M | 4.7M | 0.4% | HOLD |
| 30 | Denali Therapeutics INC. | COM | $71.6M | 3.7M | 0.4% | HOLD |
| 31 | Dianthus Therapeutics, INC. | COM | $71.5M | 852K | 0.4% | ADD |
| 32 | Monte Rosa Therapeutics, INC. | COM | $71.5M | 4.3M | 0.4% | HOLD |
| 33 | Structure Therapeutics INC. | SPONSORED ADS | $69.0M | 1.4M | 0.4% | HOLD |
| 34 | Entrada Therapeutics, INC. | COM | $64.0M | 5.1M | 0.4% | HOLD |
| 35 | Bicycle Therapeutics Plc | SPONSORED ADS | $50.5M | 10.9M | 0.3% | HOLD |
| 36 | Spyre Therapeutics, INC. | COM | $50.4M | 1.0M | 0.3% | HOLD |
| 37 | Rapport Therapeutics, INC. | COM | $48.4M | 1.5M | 0.3% | HOLD |
| 38 | Alumis INC. | COM | $44.3M | 2.0M | 0.3% | ADD |
| 39 | Mirum Pharmaceuticals, INC. | COM | $41.2M | 446K | 0.2% | NEW |
| 40 | Viridian Therapeutics, INC. | COM | $38.6M | 2.0M | 0.2% | HOLD |
| 41 | Enliven Therapeutics, INC. | COM | $35.5M | 905K | 0.2% | ADD |
| 42 | Prelude Therapeutics INC. | COM | $34.6M | 10.1M | 0.2% | HOLD |
| 43 | Dbv Technologies S.A. | SPONSORED ADS | $30.5M | 1.5M | 0.2% | HOLD |
| 44 | Design Therapeutics, INC. | COM | $27.5M | 2.6M | 0.2% | ADD |
| 45 | Centessa Pharmaceuticals Plc | SPONSORED ADS | $26.6M | 671K | 0.2% | HOLD |
| 46 | Cytomx Therapeutics, INC. | COM | $23.4M | 5.0M | 0.1% | ADD |
| 47 | Jade Biosciences, INC. | COM | $23.1M | 1.6M | 0.1% | HOLD |
| 48 | Disc Medicine, INC. | COM | $22.4M | 350K | 0.1% | ADD |
| 49 | Immunocore Holdings Plc | ADS | $22.1M | 734K | 0.1% | TRIM |
| 50 | Xenon Pharmaceuticals INC. | COM | $21.5M | 370K | 0.1% | HOLD |
| 51 | Celldex Therapeutics, INC. | COM | $21.1M | 665K | 0.1% | HOLD |
| 52 | Neurogene INC. | COM | $20.0M | 992K | 0.1% | HOLD |
| 53 | Evommune, INC. | COM SHS | $19.5M | 847K | 0.1% | NEW |
| 54 | Tectonic Therapeutic, INC. | COM | $18.8M | 608K | 0.1% | TRIM |
| 55 | Contineum Therapeutics, INC. | CL A | $18.6M | 1.4M | 0.1% | HOLD |
| 56 | Argenx Se | SPONSORED ADR | $18.4M | 25K | 0.1% | HOLD |
| 57 | Cerus Corporation | COM | $18.2M | 10.0M | 0.1% | HOLD |
| 58 | Taysha Gene Therapies, INC. | COM SHS | $17.9M | 4.0M | 0.1% | HOLD |
| 59 | Aktis Oncology, INC. | COM | $17.8M | 996K | 0.1% | NEW |
| 60 | Generate Biomedicines, INC. | COM SHS | $17.8M | 1.4M | 0.1% | NEW |
| 61 | Sionna Therapeutics, INC. | COM | $16.0M | 400K | 0.1% | HOLD |
| 62 | Dyne Therapeutics, INC. | COM | $14.7M | 813K | 0.1% | HOLD |
| 63 | Xencor, INC. | COM | $13.3M | 1.1M | 0.1% | HOLD |
| 64 | Compass Pathways Plc | SPONSORED ADS | $13.0M | 2.3M | 0.1% | NEW |
| 65 | Relay Therapeutics, INC. | COM | $11.5M | 1.2M | 0.1% | HOLD |
| 66 | Sera Prognostics, INC. | CLASS A COM | $11.2M | 5.5M | 0.1% | HOLD |
| 67 | Biontech Se | SPONSORED ADS | $10.6M | 120K | 0.1% | TRIM |
| 68 | Pharvaris N.V. | COM | $10.6M | 375K | 0.1% | HOLD |
| 69 | Arcus Biosciences, INC. | COM | $9.0M | 416K | 0.1% | ADD |
| 70 | Maplight Therapeutics, INC. | COM | $7.4M | 365K | 0.0% | HOLD |
| 71 | Absci Corporation | COM | $6.4M | 2.1M | 0.0% | HOLD |
| 72 | Wave Life Sciences LTD. | SHS | $6.0M | 823K | 0.0% | ADD |
| 73 | Vtv Therapeutics, INC. | CL A | $5.9M | 148K | 0.0% | HOLD |
| 74 | Eikon Therapeutics, INC. | COM | $5.9M | 556K | 0.0% | NEW |
| 75 | Protara Therapeutics, INC. | COM STK | $5.1M | 972K | 0.0% | HOLD |
| 76 | Sagimet Biosciences INC. | COM SER A | $5.0M | 953K | 0.0% | HOLD |
| 77 | Lb Pharmaceuticals INC. | COM SHS | $4.9M | 200K | 0.0% | HOLD |
| 78 | Verastem, INC. | COM | $3.1M | 585K | 0.0% | NEW |
| 79 | Tscan Therapeutics, INC. | COM | $2.8M | 2.8M | 0.0% | HOLD |
| 80 | Skye Bioscience, INC. | COM | $968K | 1.6M | 0.0% | ADD |
| 81 | Sana Biotechnology, INC. | COM | $894K | 310K | 0.0% | HOLD |
| 82 | Aligos Therapeutics, INC. | COM | $617K | 83K | 0.0% | HOLD |
| 83 | Tyra Biosciences, INC. | COM | $406K | 11K | 0.0% | HOLD |
| 84 | Surrozen, INC. | W EXP 8/11/2026 | $13K | 833K | 0.0% | HOLD |