Fund · 13F archive
Baker Bros. Advisors LP — 2025 Q3 holdings
Period end
Filed
Portfolio value
$13.84B
Positions
91
We track
1
| # | Company | Class | Value | Shares | % Port. | vs prior |
|---|---|---|---|---|---|---|
| 1 | Beone Medicines LTD. | SPONSORED ADS | $3.00B | 8.8M | 21.7% | |
| 2 | Incyte Corporation | COM | $2.61B | 30.7M | 18.8% | |
| 3 | Madrigal Pharmaceuticals, INC. | COM | $982.3M | 2.1M | 7.1% | |
| 4 | Insmed Incorporated | COM PAR $.01 | $965.4M | 6.7M | 7.0% | |
| 5 | Acadia Pharmaceuticals INC. | COM | $915.4M | 42.9M | 6.6% | |
| 6 | Summit Therapeutics INC. | COM | $696.7M | 33.7M | 5.0% | |
| 7 | Rhythm Pharmaceuticals, INC. | COM | $566.0M | 5.6M | 4.1% | |
| 8 | Revolution Medicines, INC. | COM | $441.6M | 9.5M | 3.2% | |
| 9 | Celcuity INC. | COM | $391.0M | 7.9M | 2.8% | |
| 10 | Kymera Therapeutics, INC. | COM | $376.5M | 6.7M | 2.7% | |
| 11 | Kodiak Sciences INC. | COM | $283.4M | 17.3M | 2.0% | |
| 12 | Alkermes Plc | SHS | $242.7M | 8.1M | 1.8% | |
| 13 | ABCLAbCellera Biologics Inc.★ | COM | $138.5M | 27.5M | 1.0% | |
| 14 | Edgewise Therapeutics, INC. | COM | $118.5M | 7.3M | 0.9% | |
| 15 | Kiniksa Pharmaceuticals International, Plc | ORD SHS CL A | $109.7M | 2.8M | 0.8% | |
| 16 | Stoke Therapeutics, INC. | COM | $108.9M | 4.6M | 0.8% | |
| 17 | Immatics N.V. | SHS | $103.0M | 12.1M | 0.7% | |
| 18 | Grail, INC. | COM | $96.4M | 1.6M | 0.7% | |
| 19 | Ideaya Biosciences, INC. | COM | $89.1M | 3.3M | 0.6% | |
| 20 | Immunovant, INC. | COM | $88.0M | 5.5M | 0.6% | |
| 21 | Immunocore Holdings Plc | ADS | $84.4M | 2.3M | 0.6% | |
| 22 | Bicycle Therapeutics Plc | SPONSORED ADS | $84.3M | 10.9M | 0.6% | |
| 23 | Ultragenyx Pharmaceutical INC. | COM | $83.4M | 2.8M | 0.6% | |
| 24 | Abivax S.A. | SPONSORED ADS | $74.4M | 876K | 0.5% | |
| 25 | Arrowhead Pharmaceuticals, INC. | COM | $57.6M | 1.7M | 0.4% | |
| 26 | Roivant Sciences LTD. | SHS | $57.0M | 3.8M | 0.4% | |
| 27 | Denali Therapeutics INC. | COM | $54.2M | 3.7M | 0.4% | |
| 28 | Merus N.V. | COM | $54.1M | 574K | 0.4% | |
| 29 | Intellia Therapeutics, INC. | COM | $47.4M | 2.7M | 0.3% | |
| 30 | Replimune Group, INC. | COM | $46.3M | 11.0M | 0.3% | |
| 31 | Rapport Therapeutics, INC. | COM | $45.9M | 1.5M | 0.3% | |
| 32 | Structure Therapeutics INC. | SPONSORED ADS | $43.6M | 1.6M | 0.3% | |
| 33 | Celcuity INC. | Note 2.75% 8/1/2031 | $40.9M | 30.8M prn | 0.3% | |
| 34 | Viridian Therapeutics, INC. | COM | $37.6M | 1.7M | 0.3% | |
| 35 | Ionis Pharmaceuticals, INC. | COM | $37.1M | 567K | 0.3% | |
| 36 | Praxis Precision Medicines, INC. | COM | $36.5M | 689K | 0.3% | |
| 37 | Monte Rosa Therapeutics, INC. | COM | $36.4M | 4.9M | 0.3% | |
| 38 | Biontech Se | SPONSORED ADS | $36.4M | 369K | 0.3% | |
| 39 | Nurix Therapeutics, INC. | COM | $35.9M | 3.9M | 0.3% | |
| 40 | Dianthus Therapeutics, INC. | COM | $31.1M | 790K | 0.2% | |
| 41 | Entrada Therapeutics, INC. | COM | $28.2M | 4.9M | 0.2% | |
| 42 | Argenx Se | SPONSORED ADR | $27.9M | 38K | 0.2% | |
| 43 | Avidity Biosciences, INC. | COM | $27.2M | 625K | 0.2% | |
| 44 | Vaxcyte, INC. | COM | $23.1M | 641K | 0.2% | |
| 45 | Disc Medicine, INC. | COM | $22.3M | 337K | 0.2% | |
| 46 | Cidara Therapeutics, INC. | COM | $21.8M | 227K | 0.2% | |
| 47 | Celldex Therapeutics, INC. | COM | $17.2M | 665K | 0.1% | |
| 48 | Neurogene INC. | COM | $17.2M | 992K | 0.1% | |
| 49 | Sera Prognostics, INC. | CLASS A COM | $16.8M | 5.5M | 0.1% | |
| 50 | Spyre Therapeutics, INC. | COM | $16.8M | 1.0M | 0.1% | |
| 51 | Cerus Corporation | COM | $15.9M | 10.0M | 0.1% | |
| 52 | Akero Therapeutics, INC. | COM | $15.4M | 325K | 0.1% | |
| 53 | Xenon Pharmaceuticals INC. | COM | $14.9M | 370K | 0.1% | |
| 54 | Dbv Technologies S.A. | SPONSORED ADS | $14.6M | 1.5M | 0.1% | |
| 55 | Prelude Therapeutics INC. | COM | $14.6M | 10.1M | 0.1% | |
| 56 | Arcellx, INC. | COMMON STOCK | $13.7M | 167K | 0.1% | |
| 57 | Cytomx Therapeutics, INC. | COM | $13.6M | 4.3M | 0.1% | |
| 58 | Taysha Gene Therapies, INC. | COM SHS | $13.1M | 4.0M | 0.1% | |
| 59 | Xencor, INC. | COM | $12.9M | 1.1M | 0.1% | |
| 60 | Design Therapeutics, INC. | COM | $12.9M | 1.7M | 0.1% | |
| 61 | Nuvalent, INC. | COM | $12.4M | 144K | 0.1% | |
| 62 | Sionna Therapeutics, INC. | COM | $11.8M | 400K | 0.1% | |
| 63 | Crinetics Pharmaceuticals, INC. | COM | $11.7M | 280K | 0.1% | |
| 64 | Viking Therapeutics, INC. | COM | $9.6M | 366K | 0.1% | |
| 65 | Pharvaris N.V. | COM | $9.4M | 375K | 0.1% | |
| 66 | Agios Pharmaceuticals, INC. | COM | $7.6M | 190K | 0.1% | |
| 67 | Sana Biotechnology, INC. | COM | $7.2M | 2.0M | 0.1% | |
| 68 | Sagimet Biosciences INC. | COM SER A | $6.5M | 953K | 0.0% | |
| 69 | Alumis INC. | COM | $6.2M | 1.6M | 0.0% | |
| 70 | Relay Therapeutics, INC. | COM | $6.1M | 1.2M | 0.0% | |
| 71 | Skye Bioscience, INC. | COM | $5.7M | 1.5M | 0.0% | |
| 72 | Heron Therapeutics, INC. | COM | $5.4M | 4.3M | 0.0% | |
| 73 | Tscan Therapeutics, INC. | COM | $5.1M | 2.8M | 0.0% | |
| 74 | Mbx Biosciences, INC. | COM | $4.9M | 278K | 0.0% | |
| 75 | Vtv Therapeutics, INC. | CL A | $3.5M | 148K | 0.0% | |
| 76 | Ventyx Biosciences, INC. | COM | $3.2M | 1.0M | 0.0% | |
| 77 | Lb Pharmaceuticals INC. | COM SHS | $3.2M | 200K | 0.0% | |
| 78 | Vir Biotechnology, INC. | COM | $3.1M | 543K | 0.0% | |
| 79 | Wave Life Sciences LTD. | SHS | $2.5M | 344K | 0.0% | |
| 80 | Enliven Therapeutics, INC. | COM | $2.4M | 115K | 0.0% | |
| 81 | Protara Therapeutics, INC. | COM STK | $2.3M | 537K | 0.0% | |
| 82 | Tectonic Therapeutic, INC. | COM | $1.6M | 100K | 0.0% | |
| 83 | Kala Bio, INC. | COM | $1.5M | 985K | 0.0% | |
| 84 | Generation Bio CO. | COM | $1.2M | 194K | 0.0% | |
| 85 | Contineum Therapeutics, INC. | CL A | $913K | 78K | 0.0% | |
| 86 | Aligos Therapeutics, INC. | COM | $814K | 83K | 0.0% | |
| 87 | Vyne Therapeutics INC. | COM | $285K | 851K | 0.0% | |
| 88 | Tyra Biosciences, INC. | COM | $148K | 11K | 0.0% | |
| 89 | Acrivon Therapeutics, INC. | COMMON STOCK | $41K | 23K | 0.0% | |
| 90 | Surrozen, INC. | W EXP 8/11/2026 | $15K | 833K | 0.0% | |
| 91 | Opthea Limited | SPONSORED ADS | $0 | 2.1M | 0.0% |